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P0300 Code: Random/Multiple Cylinder Misfire Detected

The engine computer has detected misfires happening across multiple cylinders rather than one specific cylinder — the engine is not firing cleanly on all cylinders.

What this means for driving

A misfire fault deserves prompt attention. The main vehicle risk is that unburned fuel from misfiring cylinders can overheat and damage the catalytic converter, which turns a moderate repair into an expensive one. If the engine is running very roughly, has lost significant power, or the check-engine light is flashing, that is the situation to stop driving and arrange a tow rather than continue.

When in doubt, have a mechanic assess it promptly. If any of the red-flag symptoms below are present, stop driving and arrange a tow rather than risking it.

Important: This page is general information only — not professional mechanical advice and not a diagnosis for your specific vehicle. Fault causes and severity vary by make, model, year, and condition. A qualified mechanic should confirm any diagnosis before you make driving decisions or authorize repairs.

Red-flag symptoms: stop and get help

Symptoms of P0300

Most likely causes, ranked

  1. Worn or fouled spark plugs
  2. Failing ignition coil(s)
  3. Vacuum leak letting unmetered air into the engine
  4. Fuel delivery problem — weak pump, clogged filter, or dirty injectors
  5. Low compression in one or more cylinders
  6. Faulty sensor (mass airflow, crankshaft, or camshaft position)

How a mechanic diagnoses it

Likely fixes

Repair costs vary by vehicle, region and shop. Get a quote from a local mechanic.

Which cylinder?

If your scanner also shows a cylinder-specific code, it points to where the misfire is happening:

CodeCylinder
P0301Cylinder 1
P0302Cylinder 2
P0303Cylinder 3
P0304Cylinder 4
P0305Cylinder 5
P0306Cylinder 6

Related codes

CheckMyCarCode content is general information only and is not a substitute for professional diagnosis. Trouble-code meanings are standardized for generic (P0xxx) codes, but causes, severity, and repairs vary by vehicle. If your car shows a red-flag symptom, stop driving and get professional help.